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[KD]DKC1 Rabbit mAb

Catalog #: ABZ4718
Application: WB, IF, ICC, IHC-F, IHC-P
Uniprot Id: O60832
Reactivity: Human, Mouse, Rat
Isotype: IgG

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Western blot analysis of DKC1 in HeLa(WT) and DKC1-Knockdown HeLa(KD) using DKC1 antibody.
Immunocytochemistry analysis of DKC1 (green) in K562 using DKC1 antibody,and DAPI(blue).
Western blot analysis of DKC1 in K562, C6, 3T3, Hela lysates using DKC1 antibody.
Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using DKC1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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	ABZ4718-20	2 weeks	20 µL	reduce add	$149.00	Add to Cart INQUIRE Select product before adding to cart

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	[KD]DKC1 Rabbit mAb
Accession (Primary)	O60832
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Reacts With	Human, Mouse, Rat
Calculated MW
Calculated MW: 58 kDa; Observed MW: 58 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:50-1:100; ICC/IF-1:100-1:200
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.
Target Information: ( O60832 )
Name	DKC1
Gene ID	1736
Other Names
DKC1; NOLA4; H/ACA ribonucleoprotein complex subunit DKC1; CBF5 homolog; Dyskerin; Nopp140-associated protein of 57 kDa; Nucleolar protein NAP57; Nucleolar protein family A member 4; snoRNP protein DKC1

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