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![[KD]IKK alpha Rabbit mAb ABZ4702](http://img.admebio.com/products/SEAC100001/20260405/ABZ4702-KD.jpg)
![[KD]IKK alpha Rabbit mAb ABZ4702](http://img.admebio.com/products/SEAC100001/20260405/ABZ4702-WB-1.jpg)
![[KD]IKK alpha Rabbit mAb ABZ4702](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ4702-KD.jpg)
![[KD]IKK alpha Rabbit mAb ABZ4702](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ4702-WB-1.jpg)
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4702-100 | 2 weeks | 100 µL | $499.00 |
Select product before adding to cart
|
||
| ABZ4702-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | [KD]IKK alpha Rabbit mAb |
|---|---|
| Accession (Primary) | O15111 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 85 kDa; Observed MW: 85 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:100-1:200; IP-1:10-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKβ (Ser176 and Ser180 in IKKα), which causes conformational changes, resulting in kinase activation. | |
Target Information: ( O15111 ) | |
| Name | CHUK |
| Gene ID | 1147 |
| Other Names | |
| CHUK; IKKA; TCF16; Inhibitor of nuclear factor kappa-B kinase subunit alpha; I-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B | |
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ADMEbio Team
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