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[KD]ATP6V1A Rabbit mAb

Catalog #: ABZ4778
Application: WB, IP, IHC-P
Uniprot Id: P38606
Reactivity: Human, Mouse, Rat
Isotype: IgG

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Western blot analysis of ATP6V1A in PC-12, mouse brain lysates using ATP6V1A antibody.
Western blot analysis of ATP6V1A in Hela, A549, HL-60, U251, U87-MG lysates using ATP6V1A antibody.
Immunohistochemistry analysis of paraffin-embedded Human tonsil using ATP6V1A antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	[KD]ATP6V1A Rabbit mAb
Accession (Primary)	P38606
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Reacts With	Human, Mouse, Rat
Calculated MW
Calculated MW: 68 kDa; Observed MW: 68 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-P-1:200-1:500; IP-1:20-1:50
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). May play a role in neurite development and synaptic connectivity (PubMed:29668857).
Target Information: ( P38606 )
Name	ATP6V1A
Gene ID	523
Other Names
HO68; VA68; VPP2; Vma1; ARCL2D; ATP6A1; IECEE3; ATP6V1A1

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