Hello, Sign in
My Account
My Account
New customer? Start here
![[KD]Cortactin Rabbit mAb ABZ5328](http://img.admebio.com/products/SEAC100001/20260405/ABZ5328-WB-1.jpg)
![[KD]Cortactin Rabbit mAb ABZ5328](http://img.admebio.com/products/SEAC100001/20260405/ABZ5328-IHC-2.jpg)
![[KD]Cortactin Rabbit mAb ABZ5328](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ5328-WB-1.jpg)
![[KD]Cortactin Rabbit mAb ABZ5328](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ5328-IHC-2.jpg)
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ5328-100 | 2 weeks | 100 µL | $499.00 |
Select product before adding to cart
|
||
| ABZ5328-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | [KD]Cortactin Rabbit mAb |
|---|---|
| Accession (Primary) | Q14247 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 62 kDa; Observed MW: 62-80 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:100-1:200; ICC/IF-1:500-1:1000; FC-1:20; IP-1:20-1:50 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Cortactin is an 80/85 kDa cytoskeleton protein that facilitates assembly of cortical actin. Cortactin is widely expressed in most adherent cells and is a prominent substrate of protein tyrosine kinase Src in vivo and in vitro. The protein sequence of cortactin contains multiple amino terminal tandem repeats of a unique 37 amino acid sequence, which associates with actin, and a Src homology 3 (SH3) domain at the carboxyl terminus. Between the repeat and the SH3 domain, there is an alpha helical structure followed by a proline rich region. Between the proline rich region and the SH3 domain, there are a series of Src phosphorylation sites (Tyr421, Tyr470, and Tyr486). In vitro, cortactin binds to and cross links F actin into meshworks. | |
Target Information: ( Q14247 ) | |
| Name | CTTN |
| Gene ID | 2017 |
| Other Names | |
| CTTN; EMS1; Src substrate cortactin; Amplaxin; Oncogene EMS1 | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
