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![[KD]Cyclin T1 Rabbit mAb ABZ4790](http://img.admebio.com/products/SEAC100001/20260405/ABZ4790-WB-1.jpg)
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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4790-100 | 2 weeks | 100 µL | $499.00 |
Select product before adding to cart
|
||
| ABZ4790-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | [KD]Cyclin T1 Rabbit mAb |
|---|---|
| Accession (Primary) | O60563 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 81 kDa; Observed MW: 81 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IHC-P-1:100-1:200; ICC/IF-1:200-1:500; FC-1:50-1:100; IP-1:20-1:50 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II) (PubMed:16109376, PubMed:16109377, PubMed:30134174, PubMed:35393539). Required to activate the protein kinase activity of CDK9: acts by mediating formation of liquid-liquid phase separation (LLPS) that enhances binding of P-TEFb to the CTD of RNA Pol II | |
Target Information: ( O60563 ) | |
| Name | CCNT1 |
| Gene ID | 904 |
| Other Names | |
| CCNT; CYCT1; HIVE1; CCNT 1; | |
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ADMEbio Team
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