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![[KO]VAMP8/EDB Rabbit mAb ABZ4816](http://img.admebio.com/products/SEAC100001/20260405/ABZ4816-WB-ZN.jpg)
![[KO]VAMP8/EDB Rabbit mAb ABZ4816](http://img.admebio.com/products/SEAC100001/20260405/ABZ4816-WB-1.jpg)
![[KO]VAMP8/EDB Rabbit mAb ABZ4816](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ4816-WB-ZN.jpg)
![[KO]VAMP8/EDB Rabbit mAb ABZ4816](http://img.admebio.com/products_thumb/SEAC100001/20260405/ABZ4816-WB-1.jpg)
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4816-100 | 2 weeks | 100 µL | $499.00 |
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|
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| ABZ4816-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | [KO]VAMP8/EDB Rabbit mAb |
|---|---|
| Accession (Primary) | Q9BV40 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 11 kDa; Observed MW: 15 kDa | |
| Buffer System | |
| Liquid in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:100-1:200; ICC/IF-1:100-1:200; FC-1:50-1:100; IP-1:20-1:50 | |
| Purification | |
| Affinity Chromatography | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| VAMP8, also named as endobrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE (soluble NSF-attachment protein receptor) superfamily. Characterized by a common sequence called the SNARE motif, SNARE proteins are involved in membrane fusion and vesicular transport (PMID: 11252968). VAMP8 is involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. It is required for dense-granule secretion in platelets and plays a role in regulated enzyme secretion in pancreatic acinar cells. VAMP8 is also involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. | |
Target Information: ( Q9BV40 ) | |
| Name | VAMP8 |
| Gene ID | 8673 |
| Other Names | |
| VAMP8; EDB; Endobrevin; VAMP-8 | |
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