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[KO]BTF3 Rabbit mAb

Catalog #: ABZ4786
Application: WB, IF, FC, IP, ICC, IHC-P
Uniprot Id: P20290
Reactivity: Human, Mouse, Rat
Isotype: IgG

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Western blot analysis of BTF3 in C6, 3T3 lysates using BTF3 antibody.
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using BTF3 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	[KO]BTF3 Rabbit mAb
Accession (Primary)	P20290
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Reacts With	Human, Mouse, Rat
Calculated MW
Calculated MW: 22 kDa; Observed MW: 22 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-P-1:100-1:200; ICC/IF-1:100-1:200; FC-1:100-1:200; IP-1:50-1:100
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Basic transcription factor 3 (BTF3), also known as nascent-polypeptide-associated complex (NAC) beta (NACB), belongs to the NAC-beta family. BTF3 serves as an oncogene and convey worse prognosis in gastric cancer, pancreatic cancer, osteosarcoma, cervical cancer, hypopharyngeal squamous cell carcinoma, prostate cancer , breast cancer. Due to alternative splicing, BTF3 is present in two different isoforms, BTF3a and BTF3b. BTF3a is the transcriptionally active form of BTF3, while the isoform lacking the first 44 amino acids of the BTF3a N-terminus, BTF3b, is transcriptionally inactive, two isoforms of BTF3, BTF3a and BTF3b corresponding to 23kDa and 18kDa(PMID: 23029305).
Target Information: ( P20290 )
Name	BTF3
Gene ID	689
Other Names
OK/SW-cl.8; Nascent polypeptide-associated complex subunit beta; NAC-beta; NACB; BTF3b

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