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[KO]Tuberin Rabbit mAb

Catalog #: ABZ4673
Application: WB, IP
Uniprot Id: P49815
Reactivity: Human, Mouse
Isotype: IgG

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Western blot analysis of Tuberin in HeLa(WT) and Tuberin-Knockout HeLa(KO) using Tuberin antibody.
Western blot analysis of Tuberin in Hela, A549, HL-60, U2OS lysates using Tuberin antibody.

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	ABZ4673-20	2 weeks	20 µL	reduce add	$149.00	Add to Cart INQUIRE Select product before adding to cart

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	[KO]Tuberin Rabbit mAb
Accession (Primary)	P49815
Host Species	Rabbit
Clonality	Monoclonal
Isotype	IgG
Reacts With	Human, Mouse
Calculated MW
Calculated MW: 201 kDa; Observed MW: 201 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IP-1:20-1:50
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis.
Target Information: ( P49815 )
Name	TSC2
Gene ID	7249
Other Names
LAM; TSC4; PPP1R160; TSC2

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