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>   Home   >   Products   >   Primary Antibodies   >   [KO]Cyclin E2 Rabbit mAb   

[KO]Cyclin E2 Rabbit mAb

 
Catalog #
ABZ4699
Application
WB, IF, FC, IP, ICC, IHC-P
Uniprot Id
O96020
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of Cyclin E2 in HeLa(WT) and Cyclin E2-Knockout HeLa(KO) using Cyclin E2 antibody.
  • Western blot analysis of Cyclin E2 in K562, Hela lysates using Cyclin E2 antibody.
  • Immunocytochemistry analysis of Cyclin E2(green) in Hela using Cyclin E2 antibody,and DAPI(blue)
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ4699-100 2 weeks 100 µL $499.00
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ABZ4699-20 2 weeks 20 µL $149.00
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Product Overview

Name[KO]Cyclin E2 Rabbit mAb
Accession (Primary)O96020
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 47 kDa; Observed MW: 47 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:100-1:500; ICC/IF-1:50-1:200; FC-1:20; IP-1:20-1:50
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers.

Target Information: ( O96020 )

NameCCNE2
Gene ID9134
Other Names
CCN E2; CCNE 2; CCNE2; G1/S-specific cyclin-E2; CYCE2; Cyclin E2
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