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>   Home   >   Products   >   Primary Antibodies   >   NOLC1 Rabbit mAb   

NOLC1 Rabbit mAb

 
Catalog #
ABZ2117
Application
WB, IF, FC, ICC, IHC-P
Uniprot Id
Q14978
Reactivity
Human, Mouse
Isotype
IgG
 
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  • Western blot analysis of NOLC1 in Jurkat lysates using NOLC1 antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human breast cancer using NOLC1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Immunocytochemistry analysis of NOLC1 (green) in Hela using NOLC1 antibody,and DAPI(blue)
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ2117-100 2 weeks 100 µL $499.00
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ABZ2117-20 2 weeks 20 µL $149.00
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Product Overview

NameNOLC1 Rabbit mAb
Accession (Primary)Q14978
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse
Calculated MW
Calculated MW: 74 kDa; Observed MW: 110 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:50-1:100; ICC/IF-1:200-1:500; FC-1:200-1:500
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:10567578, PubMed:26399832). Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832). Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus (PubMed:9016786). It has intrinsic GTPase and ATPase activities (PubMed:9016786).

Target Information: ( Q14978 )

NameNOLC1
Gene ID9221
Other Names
P130; Srp40; NOPP130; NOPP140; NS5ATP13; NOLC1
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