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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| NTP0019-100 | 7 days | 100 mg | $600.00 |
Select product before adding to cart
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| NTP0019-500 | 7 days | 500 mg | $1,720.00 | |||
| NTP0019-1 | 7 days | 1gr | $2,400.00 |
Product Overview | |
| Name | Cytochrome-C Bovine |
|---|---|
| Description | |
| Cytochrome-C Bovine | |
| Synonyms | |
| D-amino-acid oxidase, DAMOX, DAAO, DAO, OXDA, MGC35381. | |
| Introduction | |
| DAAO is a peroxisomal enzyme which uses FAD (flavin adenine dinucleotide) as a cofactor and oxidizes D-amino acids to the corresponding amino acids, producing ammonia and hydrogen peroxide. DAAO substrates include an extensive array of D-amino acids, but it is inactive on the naturally occurring L-amino acids. DAAO acts on a variety of D-amino acids especially on those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups; however it doesn’t act on acidic amino acids. DAAO may be involved in acid base balance in the kidney or it could act as a detoxifying agent which removes D-amino acids accumulated during aging. DAAO regulates the neuromodulator D-serine level in the brain. DAAO is highly active towards D-DOPA. Creatinine inhibits the DAAO in uremia. DAAO may also have a role in the pathophysiology of schizophrenia, but not in bipolar disorder. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The DAAO solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 20% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MRVVVIGAGV IGLSTALCIH ERYHSVLQPL DIKVYADRFT PLTTTDVAAG LWQPYLSDPN NPQEADWSQQ TFDYLLSHVH SPNAENLGLF LISGYNLFHE AIPDPSWKDT VLGFRKLTPR ELDMFPDYGY GWFHTSLILE GKNYLQWLTE RLTERGVKFF QRKVESFEEV AREGADVIVN CTGVWAGALQ RDPLLQPGRG QIMKVDAPWM KHFILTHDPE RGIYNSPYII PGTQTVTLGG IFQLGNWSEL NNIQDHNTIW EGCCRLEPTL KNARIIGERT GFRPVRPQIR LEREQLRTGP SNTEVIHNYG HGGYGLTIHW GCALEAAKLF GRILEEKKLS RMPPSHL. | |
| Precautions | |
| Cytochrome-C Bovine is for research use only and not for use in diagnostic or therapeutic procedures. | |
Background |
Bovine Cytochrome c in Health and Disease: Understanding the behavior of Cytochrome c in bovine systems has implications for veterinary medicine and livestock health. Alterations in mitochondrial function, reflected in changes in Cytochrome c dynamics, may be indicative of metabolic disorders, oxidative stress, or other pathological conditions. Bovine Cytochrome c studies contribute to our knowledge of mitochondrial dysfunction in diseases affecting cattle, potentially paving the way for diagnostic and therapeutic strategies. Challenges and Future Directions: While the study of Cytochrome c in bovine systems provides a wealth of insights, challenges persist. Fine-tuning experimental methodologies, exploring the interplay with other mitochondrial components, and deciphering the specificities in bovine systems are critical considerations for advancing our understanding. Additionally, linking changes in Cytochrome c behavior to specific physiological outcomes in cattle poses a challenge, requiring comprehensive investigations in diverse contexts. Bovine Cytochrome c emerges as a sentinel player in the intricate dance of cellular respiration, offering a window into the energetic dynamics of bovine mitochondria. Its structural insights, functional significance, and implications in health and disease position it as a central focus in understanding cellular bioenergetics in cattle. As researchers continue to unravel the molecular intricacies of bovine Cytochrome c, they not only deepen our understanding of mitochondrial function but also contribute to advancements in veterinary medicine and the optimization of livestock health, shaping the future of sustainable and healthy cattle farming practices. |
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