Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| NTP0052-10 | 7 days | 10 mg | $1,540.00 |
Select product before adding to cart
|
||
| NTP0052-20 | 7 days | 20 mg | $2,640.00 | |||
| NTP0052-40 | 7 days | 40 mg | $3,520.00 |
Product Overview | |
| Name | Thrombin |
|---|---|
| Description | |
| Human Thrombin | |
| Synonyms | |
| Coagulation Factor II (Thrombin), Prepro-Coagulation Factor II, EC 3.4.21.5, RPRGL2, THPH1, Coagulation Factor II, Prothrombin B-Chain, Serine Protease, Prothrombin, EC 3.4.21, PT, F2. | |
| Introduction | |
| Thrombin enzyme (Activated Factor IIa) is an important clotting promoter that controls the transformation of soluble fibrinogen to insoluble active fibrin strands. Thrombin is a coagulation protein and a serine protease (EC 3.4.21.5) that catalyzes many coagulation-related reactions. Thrombin triggers factor-XI, factor-V, Factor-XIII and factor-VIII. Thrombin endorses platelet activation, using activation of protease-activated receptors on the platelet. As a result of its high proteolytic specificity, thrombin has become an important biochemical protein. The thrombin cleavage site (Leu-Val-Pro-Arg-Gly-Ser) is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein, thrombin is used to cleave between the Arginine and Glycine residues of the cleavage site, efficiently removing the purification tag from the protein of interest with a high degree of specificity. | |
| Source | |
| Bovine Blood. | |
| Physical Appearance | |
| Sterile Filtered beige lyophilized (freeze-dried) powder. | |
| Formulation | |
| Lyophilized freeze dry powder formulated with glycine, CaCl2 and sodium chloride, PH 6.8. | |
| Stability | |
| Lyophilized Thrombin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Thrmbin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Biological Activity | |
| 164 US units/mg protein. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Thrombin in 0.9% NaCl. | |
| Precautions | |
| Thrombin is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
