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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| NTR0054-2 | 7 days | 2 µg | $120.00 |
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| NTR0054-10 | 7 days | 10 µg | $290.00 | |||
| NTR0054-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | NRG4 Human |
|---|---|
| Description | |
| Neuregulin-4 Human Recombinant | |
| Accession (Primary) | Q8WWG1 |
| Synonyms | |
| hng, RC3, Neurogranin, Ng, NRGN. | |
| Introduction | |
| Neurogranin (NRGN) is a calmodulin-binding protein which is expressed solely in the brain, mainly in dendritic spines. NRGN is also taking part in the protein kinase C signaling pathway by being a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. NRGN binds to calmodulin in the absence of calcium. NRGN protein’s phosphorylation by protein kinase C lowers its binding ability. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| NRGN protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH7.0), 30% glycerol 0.1mM PMSF and 1mM EDTA. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MDCCTEN ACSKPDDDIL DIPLDDPGAN AAAAKIQASF RGHMARKKIK SGERGRKGPG PGGPGGAGVA RGGAGGGPSG D. | |
| Precautions | |
| NRG4 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q8WWG1 ) | |
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ADMEbio Team
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ADMEbio Team
