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Neuropilin 1 Rabbit pAb

 
Catalog #
ABZ1543
Application
WB, IF, ICC, ELISA, IHC-P
Uniprot Id
O14786
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of Neuropilin 1 in 293 lysates using Neuropilin 1 antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human kidney using Neuropilin 1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Immunohistochemistry analysis of paraffin-embedded Human kidney using Neuropilin 1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ1543-100 2 weeks 100 µL $499.00
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ABZ1543-20 2 weeks 20 µL $149.00
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Product Overview

NameNeuropilin 1 Rabbit pAb
Accession (Primary)O14786
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 103 kDa; Observed MW: 100 kDa
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:2000; IHC:-1:100-1:300; IF-1:50-1:200; ELISA-1:20000
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.

Target Information: ( O14786 )

NameNRP1
Gene ID8829
Other Names
A5 protein; BDCA4; BLOOD DENDRITIC CELL ANTIGEN 4;
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