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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2097-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2097-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | PCBP2/hnRNP E2 Rabbit mAb |
|---|---|
| Accession (Primary) | Q15366 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 39 kDa; Observed MW: 35-45 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; ICC/IF-1:200-1:500; FC-1:100-1:200; IP-1:50-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509). | |
Target Information: ( Q15366 ) | |
| Name | PCBP2 |
| Gene ID | 5094 |
| Other Names | |
| HNRPE2; HNRNPE2; hnRNP-E2; Poly(rC)-binding protein 2; poly(rC) binding protein 2; Alpha-CP2 | |
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ADMEbio Team
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ADMEbio Team
