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PI3 Kinase p85 alpha (3H5) Mouse mAb

Catalog #: ABZ3995
Application: WB, IHC-P
Uniprot Id: P27986
Reactivity: Human, Mouse, Rat
Isotype: IgG1

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Immunohistochemistry analysis of paraffin-embedded rat Liver Tissue using PI3 Kinase p85 alpha (3H5) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemical analysis of paraffin-embedded Human tonsils using PI3 Kinase p85 alpha (3H5) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western blot analysis of PI3 Kinase p85 alpha (3H5) in THP-1, MCF-7, Goat Muscle, CHO-K1, C6, 3T3 lysates using PI3 Kinase p85 alpha (3H5) antibody
Western blot analysis of PI3 Kinase p85 alpha (3H5) in Hela, A549, HL-60, U2OS, C6 lysates using PI3 Kinase p85 alpha (3H5) antibody.

	Catalog #	Availability	Size	Quantity	Unit Price	Save For Later Wish List
	ABZ3995-100	2 weeks	100 µL	reduce add	$499.00	Add to Cart INQUIRE Select product before adding to cart
	ABZ3995-20	2 weeks	20 µL	reduce add	$149.00	Add to Cart INQUIRE Select product before adding to cart

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Datasheet
Citations
Reviews

Species Reactivity
Product Overview
Name	PI3 Kinase p85 alpha (3H5) Mouse mAb
Accession (Primary)	P27986
Host Species	Mouse
Clonality	Monoclonal
Isotype	IgG1
Reacts With	Human, Mouse, Rat
Calculated MW
Calculated MW: 84 kDa; Observed MW: 84 kDa
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:500-1:1000; IHC-1:50-1:100
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Target Information: ( P27986 )
Name	PIK3R1
Gene ID	5295
Other Names
PIK3R1; GRB1; p85; AGM7; GRB1; IMD36; p85alpha; p85-ALPHA; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha;

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