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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4535-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4535-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Phospho-Dishevelled 2 (Ser143) Rabbit mAb |
|---|---|
| Accession (Primary) | O14641 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse |
| Calculated MW | |
| Calculated MW: 79 kDa; Observed MW: 90-95 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Phosphorylated | |
| Form | |
| Liquid | |
| Background | |
| DVL2 is member of the dishevelled (dsh) protein family. DVL2 encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein in a variety of cell lines and species. DVL2 participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. It promotes internalization and degradation of frizzled proteins upon Wnt signaling. It plays a role both in canonical and non-canonical Wnt signaling. It also Plays a role in the signal transduction pathways mediated by multiple Wnt genes. | |
Target Information: ( O14641 ) | |
| Name | DVL2 |
| Gene ID | 1856 |
| Other Names | |
| DVL2; Dishevelled 2; Segment polarity protein dishevelled homolog DVL-2; DSH homolog 2; Dishevelled-2 | |
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ADMEbio Team
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ADMEbio Team
