| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4371-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4371-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Phospho-ITK (Tyr512) Rabbit pAb |
|---|---|
| Accession (Primary) | Q08881 |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse |
| Calculated MW | |
| Calculated MW: 72 kDa; Observed MW: 72 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:2000; IHC-1:100-1:300; IF-1:50-1:200; ELISA-1:5000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Phosphorylated | |
| Form | |
| Liquid | |
| Background | |
| Interleukin-2 inducible T-cell kinase (Itk, Emt or Tsk) is a member of the non-receptor protein tyrosine kinases. Family members of Itk include Tec, Btk, Rlk and Bmx and are all defined by a common structure: an amino-terminal PH domain, a Tec-homology domain and a SH3 and SH2 domain followed by a carboxy-terminal kinase domain. Tec, Rlk and Itk are expressed in T cells and activated in response to T cell receptor (TCR) engagement. | |
Target Information: ( Q08881 ) | |
| Name | ITK |
| Gene ID | 3702 |
| Other Names | |
| ITK; EMT; LYK; Tyrosine-protein kinase ITK/TSK; Interleukin-2-inducible T-cell kinase; IL-2-inducible T-cell kinase; Kinase EMT; T-cell-specific kinase; Tyrosine-protein kinase Lyk | |
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ADMEbio Team
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ADMEbio Team