| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ4400-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ4400-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Phospho-p27 KIP 1 (Ser10) Rabbit mAb |
|---|---|
| Accession (Primary) | P46527 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 22 kDa; Observed MW: 27 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:50-1:100; IP-1:20-1:50 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Phosphorylated | |
| Form | |
| Liquid | |
| Background | |
| The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. | |
Target Information: ( P46527 ) | |
| Name | CDKN1B |
| Gene ID | 1027 |
| Other Names | |
| CDKN1B; KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1 | |
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ADMEbio Team
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ADMEbio Team