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QK1 Rabbit mAb

 
Catalog #
ABZ1904
Application
WB, IF, IP, ICC
Uniprot Id
Q96PU8
Reactivity
Human, Mouse
Isotype
IgG
 
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  • Western blot analysis of QK1 in 3T3, rat brain lysates using QK1 antibody.
  • Western blot analysis of QK1 in K562 lysates using QK1 antibody.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ1904-100 2 weeks 100 µL $499.00
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ABZ1904-20 2 weeks 20 µL $149.00
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Product Overview

NameQK1 Rabbit mAb
Accession (Primary)Q96PU8
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse
Calculated MW
Calculated MW: 38 kDa; Observed MW: 38 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; ICC/IF-1:50-1:100; IP-1:10-1:100
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor .

Target Information: ( Q96PU8 )

NameQKI
Gene ID9444
Other Names
QK; Hqk; QK1; QK3; hqkI; DKFZp586I0923; HKQ; Homolog of mouse quaking QKI KH domain RNA binding protein;
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