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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0020-2 | 7 days | 2 µg | $120.00 |
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| RCP0020-10 | 7 days | 10 µg | $290.00 | |||
| RCP0020-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | AFAP1 Human |
|---|---|
| Description | |
| Actin Filament Associated Protein 1 Human Recombinant | |
| Accession (Primary) | Q8N556 |
| Synonyms | |
| HBGF-1, ECGF-beta, FIBP, FGFIBP, FIBP-1, ECGF, ECGFA, GLIO703, FGF1, FGF-a. | |
| Introduction | |
| Acidic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. | |
| Source | |
| Bovine Brain. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Each 5 µg aFGF were lyophilized from 0.5ml solution containing 1mM sodium phosphate, pH 7 after filtration over a low binding membrane. | |
| Stability | |
| Lyophilized aFGF although stable at room temperature for 2 weeks, should be stored desiccated below -18°C. Upon reconstitution aFGF should be stored at 4°C between 2-3 weeks and for future use below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 90%. | |
| Biological Activity | |
| Stimulates growth of bovine capillary endothelial cells by 3-5 fold over 5% calf serum at 10-25ng/ml FGF. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized aFGF in sterile 50mM Na2HPO4 pH-7, and 0.5% albumin. The Recommended concentration in cell culture: 1-20ng/ml. | |
| Precautions | |
| AFAP1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q8N556 ) | |
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ADMEbio Team
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