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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0071-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP0071-20 | 7 days | 20 µg | $290.00 | |||
| RCP0071-1 | 7 days | 1 mg | $3,600.00 |
Product Overview | |
| Name | ANXA5 Human |
|---|---|
| Description | |
| Annexin A5 Human Recombinant | |
| Accession (Primary) | P08758 |
| Synonyms | |
| Annexin A5, ENX2, Placental Anticoagulant Protein 4, Placental Anticoagulant Protein I, Vascular Anticoagulant-Alpha, Thromboplastin Inhibitor, Calphobindin I, Anchorin CII, Endonexin II, Lipocortin V, Annexin V, Annexin-5, VAC-Alpha, RPRGL3, CBP-I, PAP-I, ANX5, PP4, Epididymis Secretory Protein Li 7, HEL-S-7. | |
| Introduction | |
| ANXA5 is a member of the annexin family of calcium-dependent phospholipid binding proteins which are involved in membrane-related activity along exocytotic and endocytotic pathways. ANXA5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel properties and takes part in cellular signal transduction, inflammation, growth and differentiation. ANXA5 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. ANXA5 regulates coagulability in the blood stream by binding to phosphatidylserine and sulfatide. ANXA5 protects sinsuoidal endothelial cells from ischemia reperfusion damage. ANXA5 is necessary for normal CFTR chloride channel activity. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| ANXA5 protein solution (1mg/ml) containing Phosphate Buffered Saline, 10% glycerol and 1mM DTT. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSP MGS MATRGTV TDFPGFDGRA DAEVLRKAMK GLGTDEDSIL NLLTSRSNAQ RQEIAQEFKT LFGRDLVDDL KSELTGKFEK LIVAMMKPSR LYDAYELKHA LKGAGTDEKV LTEIIASRTP EELSAIKQVY EEEYGSNLED DVVGDTSGYY QRMLVVLLQA NRDPDTAIDD AQVELDAQAL FQAGELKWGT DEEKFITIFG TRSVSHLRRV FDKYMTISGF QIEETIDRET SGNLEQLLLA VVKSIRSIPA YLAETLYYAM KGAGTDDHTL IRVVVSRSEI DLFNIRKEFR KNFATSLYSM IKGDTSGDYK KALLLLCGGE DD. | |
| Precautions | |
| ANXA5 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P08758 ) | |
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ADMEbio Team
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