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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0102-5 | 7 days | 5 µg | $120.00 |
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| RCP0102-20 | 7 days | 20 µg | $290.00 | |||
| RCP0102-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | ARHGEF39 Human |
|---|---|
| Description | |
| Rho Guanine Nucleotide Exchange Factor 39 Human Recombinant | |
| Accession (Primary) | Q8N4T4 |
| Synonyms | |
| ARFL1. | |
| Introduction | |
| ARL1 is part of the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally associated to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, control intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. ARL1 is a weak stimulator of PLD and CT in a phospholipid dependent manner. ARL1 is a GTP-binding protein that has low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. ARL1 is involved in the Golgi apparatus. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| The ARL1 solution (0.25mg/ml) containing 20mM Tris-HCl pH-8, 2mM DTT, 100mM NaCl and 40% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGGFFSSIFS SLFGTREMRI LILGLDGAGK TTILYRLQVG EVVTTIPTIG FNVETVTYKN LKFQVWDLGG QTSIRPYWRC YYSNTDAVIY VVDSCDRDRI GISKSELVAM LEEEELRKAI LVVFANKQDM EQAMTSSEMA NSLGLPALKD RKWQIFKTSA TKGTGLDEAM EWLVETLKSR Q. | |
| Precautions | |
| ARHGEF39 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q8N4T4 ) | |
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ADMEbio Team
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ADMEbio Team
