| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0126-5 | 7 days | 5 µg | $120.00 |
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| RCP0126-20 | 7 days | 20 µg | $290.00 | |||
| RCP0126-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | ASF1A Human |
|---|---|
| Description | |
| ASF1 Anti-Silencing Function 1 Homolog A Human Recombinant | |
| Accession (Primary) | Q9Y294 |
| Immunogen | |
| Anti-human ASF1B mAb, clone PAT1D4AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ASF1B protein (1-202 amino acids) purified from E. coli. | |
| Synonyms | |
| Histone chaperone ASF1B, Anti-silencing function protein 1 homolog B, hAsf1, hAsf1b, CCG1-interacting factor A-II, CIA-II, hCIA-II, ASF1B. | |
| Introduction | |
| ASF1 Anti-Silencing Function 1 Homolog B (ASF1B) belongs to the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 protein in yeast. ASF1B is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may have a crucial role in modulating the nucleosome structure of chromatin by guaranteeing a regular supply of histones at sites of nucleosome assembly. ASF1B cooperates with CAF-1 (chromatin assembly factor 1) to stimulate replication-dependent chromatin assembly. ASF1B is highly expressed in the testis and at lower levels in colon, small intestine and thymus. ASF1B is necessary for spermatogenesis. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide. | |
| Applications | |
| The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PAT1D4AT. | |
| Ig Subclass | |
| Mouse IgG 2b heavy chain and k light chain. | |
| Purification Method | |
| ASF1B antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| ASF1A Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9Y294 ) | |
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ADMEbio Team
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