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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0153-2 | 7 days | 2 µg | $120.00 |
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| RCP0153-10 | 7 days | 10 µg | $290.00 | |||
| RCP0153-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | AZGP1 Human, Sf9 |
|---|---|
| Description | |
| Alpha-2-Glycoprotein 1 Zinc-Binding Human Recombinant, Sf9 | |
| Accession (Primary) | P25311 |
| Synonyms | |
| Beta Polypeptide, NGF, NGFB, HSAN5, Beta-NGF, MGC161426, MGC161428. | |
| Introduction | |
| NGF-beta has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The beta-NGF protein was lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA). | |
| Stability | |
| Lyophilized Beta-NGF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution NGF-Beta should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MSSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA. | |
| Biological Activity | |
| The ED 50 , calculated by its ability to stimulate proliferation of TF-1 cells and is typically 1.31 ng/ml, corresponding to a specific activity of 7.6x10 5 units/mg. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized NGF-b in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| References | |
| Title: u-Opioid receptor activation in live cells Publication: Journal 22.10 (2008): 3537-3548. Link: b NGF prospec publication | |
| Precautions | |
| AZGP1 Human, Sf9 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P25311 ) | |
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ADMEbio Team
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ADMEbio Team
