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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0156-50 | 7 days | 50 µg | $1,400.00 |
Select product before adding to cart
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| RCP0156-100 | 7 days | 100 µg | $2,000.00 | |||
| RCP0156-1 | 7 days | 1 mg | $7,200.00 |
Product Overview | |
| Name | B.Microti p41 |
|---|---|
| Description | |
| Babesia Microti p41 Recombinant | |
| Immunogen | |
| Purified mouse LN B cells. | |
| Synonyms | |
| LCA, PTPRC, LY5, B220, CD45R, T200, GP180, PROTEIN-TYROSINE PHOSPHATASE, RECEPTOR-TYPE C. | |
| Introduction | |
| B220 (CD45R) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. B220 (CD45R) is required for t-cell activation through the antigen receptor. The first ptpase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Staining antibody. For staining, use 10 µl/1,000,000 cells. | |
| Type | |
| Rat Anti Mouse Monoclonal. | |
| Clone | |
| mB220. | |
| Ig Subclass | |
| Rat IgM. | |
| Purification Method | |
| Ion exchange column. | |
| Storage Procedures | |
| Lyophilized: store at 4C. After reconstitution, if not intended for use within a month, aliquot and store at -20C. | |
| Available Conjugates | |
| This antibody is only available as purified antibody. | |
| Precautions | |
| B.Microti p41 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
