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BAALC Human

Brain and Acute Leukemia Cytoplasmatic Human Recombinant

 
Catalog #
RCP0162
Uniprot Id
Q8WXS3
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP0162-2 7 days 2 µg $120.00
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RCP0162-10 7 days 10 µg $290.00
RCP0162-1 7 days 1 mg $8,320.00
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Product Overview

NameBAALC Human
Description
Brain and Acute Leukemia Cytoplasmatic Human Recombinant
Accession (Primary)Q8WXS3
Synonyms
BRISC and BRCA1-A complex member 1, Mediator of RAP80 interactions and targeting subunit of 40 kDa, New component of the BRCA1-A complex, BABAM1, C19orf62, MERIT40, NBA1, HSPC142, BRISC And BRCA1 A Complex Member 1.
Introduction
BRISC And BRCA1 A Complex Member 1, also known as BABAM1, is a part of the BRCA1-A complex. The BRCA1-A complex identifies 'Lys-63'- linked ubiquitinated histones H2A and H2AX at DNA lesions sites and also holds deubiquitinase activity which removes in particular 'Lys-63'-linked ubiquitin on histones H2A and H2AX. BABAM1 is necessary to preserve the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36 component.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
BABAM1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
Purity
Greater than 85% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGS MEVAEPS SPTEEEEEEE EHSAEPRPRT RSNPEGAEDR AVGAQASVGS RSEGEGEAAS ADDGSLNTSG AGPKSWQVPP PAPEVQIRTP RVNCPEKVII CLDLSEEMSL PKLESFNGSK TNALNVSQKM IEMFVRTKHK IDKSHEFALV VVNDDTAWLS GLTSDPRELC SCLYDLETAS CSTFNLEGLF SLIQQKTELP VTENVQTIPP PYVVRTILVY SRPPCQPQFS LTEPMKKMFQ CPYFFFDVVY IHNGTEEKEE EMSWKDMFAF MGSLDTKGTS YKYEVALAGP ALELHNCMAK LLAHPLQRPC QSHASYSLLE EEDEAIEVEA TV.
Precautions
BAALC Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( Q8WXS3 )

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