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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0221-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP0221-10 | 7 days | 10 µg | $290.00 | |||
| RCP0221-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | BIRC7 Human, (1-280 a.a.) |
|---|---|
| Description | |
| Baculoviral IAP Repeat-Containing 7 (1-280 a.a.) Human Recombinant | |
| Accession (Primary) | Q96CA5 |
| Introduction | |
| Bivalirudin directly inhibits thrombin by specifically binding as well to the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Bivalirudin is a specific and reversible direct thrombin inhibitor. Thrombin, which is a serine protease, plays a central role in the thrombotic process; it cleaves fibrinogen into fibrin monomers and activates Factor XIII to Factor XIIIa, allowing fibrin to develop a covalently cross-linked structure which stabilizes the thrombus. Thrombin also activates Factors V and VIII, which promotes further thrombin generation, activates platelets, stimulating aggregation and granule release. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The protein (1mg/ml) was lyophilized with 0.5mg Manntiol and sodium hydroxide 50 µg pH-5.5. | |
| Stability | |
| Lyophilized Bivalirudin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Bivalirudin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized Bivalirudin in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| BIRC7 Human, (1-280 a.a.) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q96CA5 ) | |
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ADMEbio Team
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ADMEbio Team
