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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0268-2 | 7 days | 2 µg | $120.00 |
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| RCP0268-10 | 7 days | 10 µg | $290.00 | |||
| RCP0268-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | C1QTNF2 Human |
|---|---|
| Description | |
| Complement C1q Tumor Necrosis Factor-Related Protein 2 Human Recombinant | |
| Accession (Primary) | Q9BXJ5 |
| Synonyms | |
| Complement C1q tumor necrosis factor-related protein 3, Secretory protein CORS26, C1QTNF3, CTRP3, Cors, Corcs, CORS26, FLJ37576, Cartducin. | |
| Introduction | |
| C1QTNF3 also called Cartducin is a novel angiogenic factor in the formation of neointima following angioplasty. C1QTNF3 a paralog of Acrp30 (adiponectin). C1QTNF3 is a secretory protein produced by chondrogenic precursors & proliferating chondrocytes, and belongs to a novel C1q family of proteins. Cartducin promotes the growth of mesenchymal chondroprogenitor cells & chondrosarcoma-derived chondrocytic cells in vitro. Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways. C1QTNF3 promotes proliferation & the migration of endothelial cells. | |
| Source | |
| Escherichia Coli. | |
| Formulation | |
| Human C1QTNF3 was filtered (0.4 µm) and lyophilized in 0.5 mg/ml in 0.05M Acetate buffer pH4. | |
| Stability | |
| Store lyophilized C1QTNF3 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted C1QTNF3 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| The purity of C1QTNF3 is greater than 95% as determined by SDS PAGE. | |
| Amino acid sequence | |
| MKHHHHHHAS QDEYMESPQT GGLPPDCSKC CHGDYSFRGY QGPPGPPGPP GIPGNHGNNG NNGATGHEGA KGEKGDKGDL GPRGERGQHG PKGEKGYPGI PPELQIAFMA SLATHFSNQN SGIIFSSVET NIGNFFDVMT GRFGAPVSGV YFFTFSMMKH EDVEEVYVYL MHNGNTVFSM YSYEMKGKSD TSSNHAVLKL AKGDEVWLRM GNGALHGDHQ RFSTFAGFLLFETK. | |
| Solubility | |
| It is recommended to add 0.1M Acetate buffer pH4 to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10 µg/ml. In higher concentrations the solubility of the protein is limited. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. | |
| Precautions | |
| C1QTNF2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9BXJ5 ) | |
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