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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0274-2 | 7 days | 2 µg | $120.00 |
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| RCP0274-10 | 7 days | 10 µg | $290.00 | |||
| RCP0274-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | C1QTNF9 Human |
|---|---|
| Description | |
| Complement C1q Tumor Necrosis Factor-Related Protein 9 Human Recombinant | |
| Accession (Primary) | P0C862 |
| Synonyms | |
| Complement C1r subcomponent, Complement component 1 subcomponent r, C1R. | |
| Introduction | |
| C1r enzyme is the activated form of C1r proenzyme which is inactive zymogen until C1 is activated.C1r is a subunit of the C1 complex which is the first complement component in the classical pathway of complement. C1 is a non-covalent calcium-dependent complex containing1 C1q, 2 C1r and 2 C1s molecules.Each C1q bindsthe Fc domains of IgG or IgM by using2 or more of its six arms. The binding of multiple arms to immune complexes causesthe production of 2 proteases that cleave and activate the 2 C1s protease zymogens in the complex by the C1r proteins. The activation of C1r results from cleavage of C1r into 2 fragments of 57,000 and 35,000 Dalton. | |
| Source | |
| Human Plasma. | |
| Physical Appearance | |
| Sterile Filtered solution. | |
| Formulation | |
| (1mg/ml) 140mM NaCl, 10mM Imidazole and 8mM EDTA, pH 7.4. | |
| Stability | |
| Human C1r is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Human Virus Test | |
| Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV, HTLV-I/II, STS and HBSAG. | |
| Precautions | |
| C1QTNF9 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P0C862 ) | |
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ADMEbio Team
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ADMEbio Team
