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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0286-10 | 7 days | 10 µg | $770.00 |
Select product before adding to cart
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| RCP0286-50 | 7 days | 50 µg | $2,090.00 | |||
| RCP0286-100 | 7 days | 100 µg | $2,640.00 |
Product Overview | |
| Name | C3b Mouse |
|---|---|
| Description | |
| Complement C3b Mouse | |
| Accession (Primary) | P01027 |
| Synonyms | |
| Complement C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, C3, CPAMD1. | |
| Source | |
| Rabbit serum. | |
| Physical Appearance | |
| Sterile Filtered solution. | |
| Formulation | |
| C3b Rabbit solution contains PBS, pH 7.2. | |
| Stability | |
| C3b is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 93.0% as determined by SDS-PAGE. | |
| Background | |
| Rabbit C3b serves as a critical opsonin, enhancing the recognition and engulfment of pathogens and immune complexes by phagocytic cells. Through its covalent attachment to target surfaces, C3b facilitates the recognition of foreign antigens and promotes their clearance by the immune system. C3b contributes to the inflammatory response by generating C5 convertase complexes, leading to the cleavage of C5 into C5a and C5b. C5a is a potent chemoattractant and activator of immune cells, promoting the recruitment of neutrophils and macrophages to sites of infection or tissue damage. | |
| Precautions | |
| C3b Mouse is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P01027 ) | |
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ADMEbio Team
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ADMEbio Team
