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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0339-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP0339-20 | 7 days | 20 µg | $290.00 | |||
| RCP0339-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | CARD17 Human |
|---|---|
| Description | |
| Caspase Recruitment Domain Family, Member 17 Human Recombinant | |
| Accession (Primary) | Q5XLA6 |
| Synonyms | |
| Caspase recruitment domain family member 18, ICEBERG, pseudo-ICE, UNQ5804, Caspase-1 inhibitor Iceberg, ICEBERG caspase-1 inhibitor. | |
| Introduction | |
| CARD18 belongs to the death-domain-fold superfamily which is induced by proinflammatory stimuli. CARD18 contains basically only a Caspase recruitment domain, inhibits generation of IL-1b by cooperating with caspase-1 and inhibiting connotation with RIP 2. The connotation of CARD18 to caspase-1 is enabled by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. | |
| Source | |
| E.coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The LSM3 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM Nacl, 1mM DTT and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MADQLLRKKR RIFIHSVGAG TINALLDCLL EDEVISQEDM NKVRDENDTV MDKARVLIDL VTGKGPKSCC KFIKHLCEED PQLASKMGLH | |
| Precautions | |
| CARD17 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q5XLA6 ) | |
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ADMEbio Team
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ADMEbio Team
