Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0344-2 | 7 days | 2 µgg | $120.00 |
Select product before adding to cart
|
||
| RCP0344-10 | 7 days | 10 µg | $290.00 | |||
| RCP0344-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | CBFB HUman |
|---|---|
| Description | |
| Core Binding Factor Beta Human Recombinant | |
| Accession (Primary) | Q13951 |
| Immunogen | |
| Anti-human CBR1 mAb is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CBR1 protein. | |
| Synonyms | |
| Carbonyl Reductase 1, SDR21C1, Prostaglandin-E(2) 9-reductase, NADPH-dependent carbonyl reductase 1, CBR, hCBR1, 15-hydroxyprostaglandin dehydrogenase, CRN. | |
| Introduction | |
| CBR1 is a NADPH-dependent, monomeric, and cytosolic enzyme which is related to a family of short-chain dehydrogenases/reductases. CBR1 protein (277 a.a.) is broadly spread in human tissues such as liver, epidermis, stomach, small intestine, kidney, neuronal cells, and smooth muscle fiber. CBR1 metabolizes numerous toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E). | |
| Formulation | |
| 1mg/ml containing Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide. | |
| Applications | |
| The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:1,000. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| 4E12. | |
| Ig Subclass | |
| Mouse IgG2a heavy chain and Kappa light chain | |
| Purification Method | |
| Recombinant human CBR1 (1-277 aa ) purified from E. coli | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| CBFB HUman is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q13951 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
