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CBX1 Human

Chromobox Homolog 1 Human Recombinant

 
Catalog #
RCP0345
Uniprot Id
P83916
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP0345-5 7 days 5 µg $120.00
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RCP0345-20 7 days 20 µg $290.00
RCP0345-1 7 days 1 mg $4,320.00
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Product Overview

NameCBX1 Human
Description
Chromobox Homolog 1 Human Recombinant
Accession (Primary)P83916
Synonyms
Chromobox homolog 3 (Drosophila HP1 gamma), Heterochromatin protein 1 homolog gamma, Modifier 2 protein, HP1 gamma homolog, HECH, HP1Hs-gamma.
Introduction
CBX3 takes part in transcriptional silencing in heterochromatin-like complexes. CBX3 identifies and binds histone H3 tails methylated at 'Lys-9', thereby create an epigenetic repression. Additionally, CBX3 takes part in the formation of functional kinetochore by interacting with MIS12 complex proteins.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The CBX3 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM Nacl, 1mM DTT and 20% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSH MASNKT TLQKMGKKQN GKSKKVEEAE PEEFVVEKVL DRRVVNGKVE YFLKWKGFTD ADNTWEPEEN LDCPELIEAF LNSQKAGKEK DGTKRKSLSD SESDDSKSKK KRDAADKPRG FARGLDPERI IGATDSSGEL MFLMKWKDSD EADLVLAKEA NMKCPQIVIA FYEERLTWHS CPEDEAQ.
Precautions
CBX1 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( P83916 )

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