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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0400-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP0400-20 | 7 days | 20 µg | $290.00 | |||
| RCP0400-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | CFB Human |
|---|---|
| Description | |
| Complement Factor B Human Recombinant | |
| Accession (Primary) | P00751 |
| Synonyms | |
| CFB, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, BF, BFD, AHUS4, ARMD14, CFAB, CFBD, FB, FBI12, GBG, H2-Bf. | |
| Introduction | |
| Complement Factor B, also known as CFB, encodes complement factor B which is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Once the alternative pathway is activated it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which connects with C3b to form the alternative pathway C3 convertase. Also, Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. | |
| Source | |
| Human Plasma. | |
| Physical Appearance | |
| Sterile filtered solution. | |
| Formulation | |
| CFB protein solution contains 10mM Sodium phosphate and 145mM NaCl, pH 7.2. | |
| Stability | |
| CFB Human is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Human Virus Test | |
| Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV and HBSAG. | |
| Precautions | |
| CFB Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P00751 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
