Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0404-10 | 7 days | 10 µg | $770.00 |
Select product before adding to cart
|
||
| RCP0404-50 | 7 days | 50 µg | $2,090.00 | |||
| RCP0404-100 | 7 days | 100 µg | $2,640.00 |
Product Overview | |
| Name | CFB-b Human |
|---|---|
| Description | |
| Complement Factor B Fragment b Human | |
| Accession (Primary) | P00751 |
| Synonyms | |
| Complement factor D, Adipsin, C3 convertase activator, Properdin factor D, CFD, DF, PFD. | |
| Introduction | |
| CFD is an important component of the alternative pathway of complement activation. CFD cleaves and activates factor B when it binds C3b or a C3b-like protein such as C3 or CVF. CFD is a serine protease that exists as a mature protease, but it exhibits a highly restricted specificity and it appears to be substrate activated. CFD cleaves factor B bound to C3b leading to the release of the Ba fragment and leaving the Bb fragment bound to C3b. The C3b,Bb complex is called a C3 or C5 convertase because it converts these proteins to their active forms by cleaving off the small peptides C3a and C5a, respectively. | |
| Source | |
| Human Plasma. | |
| Physical Appearance | |
| Sterile filtered solution. | |
| Formulation | |
| CFD protein solution contains 10mM Sodium phosphate and 145mM NaCl, pH 7.3. | |
| Stability | |
| CFD Human is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Human Virus Test | |
| Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV and HBSAG. | |
| Precautions | |
| CFB-b Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P00751 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
