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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0407-10 | 7 days | 10 µg | $700.00 |
Select product before adding to cart
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| RCP0407-50 | 7 days | 50 µg | $1,900.00 | |||
| RCP0407-100 | 7 days | 100 µg | $2,400.00 |
Product Overview | |
| Name | CFH Rat |
|---|---|
| Description | |
| Complement Factor H Rat | |
| Accession (Primary) | P08603 |
| Synonyms | |
| Complement factor I, C3B/C4B inactivator, CFI, IF. | |
| Introduction | |
| CFI cleaves and inactivates C3b and C4b. CFI is inactive without a cofactor such as the soluble factor H and C4b binding protein. CFI cleaves the alpha-peptide chain of C3b and C4b when these binds1 of the cofactors. This cleavage inactivates all of the complement activating functions of these proteins producing iC3b and iC4b.CFI cleaves the alpha chain of C3b twice and this releases a small fragment called C3f. CFI can cleave iC3b releasing C3c from C3dg in the presence of CR1.C4b is cleaved rapidly at 2 sites separating C4c from C4d. | |
| Source | |
| Human Plasma. | |
| Physical Appearance | |
| Sterile filtered solution. | |
| Formulation | |
| CFI protein solution contains Sodium phosphate, pH 7.2. | |
| Stability | |
| CFI Human is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 93.0% as determined by SDS-PAGE. | |
| Human Virus Test | |
| Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV and HBSAG. | |
| Precautions | |
| CFH Rat is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P08603 ) | |
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ADMEbio Team
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