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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0409-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP0409-20 | 7 days | 20 µg | $290.00 | |||
| RCP0409-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | CFL1 Human |
|---|---|
| Description | |
| Cofilin-1 Human Recombinant | |
| Accession (Primary) | P23528 |
| Synonyms | |
| Cofilin-2, Cofilin- muscle isoform, CFL2, NEM7. | |
| Introduction | |
| CFL2 protein is a member of the actin-binding proteins ADF family which contains 1 ADF-H domain. Cofilin is a broadly distributed intracellular actin-modulating protein which binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Defects in the CFL2 gene are the cause of nemaline myopathy type 7 (NEM7). | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| CFL2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 10% glycerol and 50mM NaCl. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL. | |
| Precautions | |
| CFL1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P23528 ) | |
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ADMEbio Team
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ADMEbio Team
