| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0412-5 | 7 days | 5 µg | $120.00 |
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| RCP0412-20 | 7 days | 20 µg | $290.00 | |||
| RCP0412-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | CFP Human |
|---|---|
| Description | |
| Complement Factor Properdin Human Recombinant | |
| Accession (Primary) | P27918 |
| Synonyms | |
| Properdin, Complement factor P, CFP, PFC, Complement factor properdin, BFD, PFD, Properdin. | |
| Introduction | |
| Complement Factor Properdin (CFP) which is a plasma glycoprotein, is a positive regulator of the alternative complement pathway of the innate immune system. CFP binds and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that eventually ends with formation of the membrane attack complex and lysis of the target cell. Mutations in CFP lead to 2 forms of properdin deficiency that cause high susceptibility to meningococcal infections. | |
| Source | |
| Human Plasma. | |
| Physical Appearance | |
| Sterile filtered solution. | |
| Formulation | |
| CFP solution contains 10mM Sodium phosphate and 145mM NaCl, pH 7.3. | |
| Stability | |
| CFP Human is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Human Virus Test | |
| Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV, HTLV-I &II, STS and HBSAG. | |
| Precautions | |
| CFP Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P27918 ) | |
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