| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0417-2 | 7 days | 2 µg | $120.00 |
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| RCP0417-10 | 7 days | 10 µg | $290.00 | |||
| RCP0417-0.1 | 7 days | 0.1 mg | $1,920.00 |
Product Overview | |
| Name | CHCHD3 Human |
|---|---|
| Description | |
| Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 Human Recombinant | |
| Accession (Primary) | Q9NX63 |
| Synonyms | |
| Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 7, Coiled-Coil-Helix-Coiled-Coil-Helix Domain-Containing Protein 7, COX23 Cytochrome C Oxidase Assembly Homolog (S. Cerevisiae), COX23 Cytochrome C Oxidase Assembly Homolog , COX23, Coiled-coil-helix-coiled-coil-helix domain-containing protein 7. | |
| Introduction | |
| Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 7, also known as CHCHD7 is a newly recognized member of a multifamily of proteins which contains a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain. The biological function of CHCHD7 is unknown and the gene has up till now not been connected with neoplasia. In addition, CHCHD7 & PLAG1 are located head-to-head about 500 bp apart in 8q12. Molecular analyses of twenty seven tumors exposed CHCHD7-PLAG1 fusions in three tumors, two of them had t(6;8) and t(8;15) translocations as a singular anomalies and one a normal karyotype. | |
| Source | |
| E.coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| CHCHD7 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS MHQTRTG KKTVRMPSVT QRLRDPDINP CLSESDASTR CLDENNYDRE RCSTYFLRYK NCRRFWNSIV MQRRKNGVKP FMPTAAERDE ILRAVGNMPY. | |
| Precautions | |
| CHCHD3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NX63 ) | |
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