| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0434-5 | 7 days | 5 µg | $120.00 |
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| RCP0434-20 | 7 days | 20 µg | $290.00 | |||
| RCP0434-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | CHRAC1 Human |
|---|---|
| Description | |
| Chromatin Accessibility Complex 1 Human Recombinant | |
| Accession (Primary) | Q9NRG0 |
| Synonyms | |
| Cholinergic Receptor, Nicotinic, Alpha 3 (Neuronal), Cholinergic Receptor, Nicotinic, Alpha Polypeptide 3, NACHRA3, LNCR2, PAOD2, Neuronal Nicotinic Acetylcholine Receptor, Alpha3 Subunit, Neuronal Acetylcholine Receptor Subunit Alpha-3, Acetylcholine Receptor, Alpha 3 (Neuronal), Nicotinic, Neuronal acetylcholine receptor subunit alpha-3. | |
| Introduction | |
| Cholinergic Receptor Nicotinic Alpha 3, also known as CHRNA3 is part of the nicotinic acetylcholine receptor family. Proteins of this family form pentameric complexes comprised of both alpha & beta subunits. Furthermore, CHRNA3 is ligand-gated ions channel which prticipates in neurotransmission. CHRNA3 has been associated with an increased risk of smoking initiation as well as an increased susceptibility to lung cancer. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| CHRNA3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 80.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS SEAEHRL FERLFEDYNE IIRPVANVSD PVIIHFEVSM SQLVKVDEVN QIMETNLWLK QIWNDYKLKW NPSDYGGAEF MRVPAQKIWK PDIVLYNNAV GDFQVDDKTK ALLKYTGEVT WIPPAIFKSS CKIDVTYFPF DYQNCTMKFG SWSYDKAKID LVLIGSSMNL KDYWESGEWA IIKAPGYKHD IKYNCCEEIY PDITYSLYIR RL. | |
| Precautions | |
| CHRAC1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NRG0 ) | |
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