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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0441-5 | 7 days | 5 µg | $120.00 |
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| RCP0441-20 | 7 days | 20 µg | $290.00 | |||
| RCP0441-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | CISD1 Human |
|---|---|
| Description | |
| CDGSH Iron Sulfur Domain 1 Human Recombinant | |
| Accession (Primary) | Q9NZ45 |
| Synonyms | |
| MRG1, P35SRJ, CIT-ED2, MSG-related protein 1, MRG-1, CITED2. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Each mg was lyophilized with 1xPBS, 0.4% SDS and 4mM DTT. | |
| Stability | |
| Store lyophilized CITED2 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Solubility | |
| It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture. | |
| Background | |
| CITED2 also known as Cbp/p300-Interacting Trans activator 2 is an important transcriptional cofactor which is involved in multiple organ development. CITED2 is part of the CITED family which take an important role in gene regulation & cellular signalling. CITED2 is a cAMP-responsive element-binding protein interacting transcriptional modulator and an anticipated negative regulator for Recombinant human CITED2 protein 1 hypoxia-inducible factor (HIF) -1alpha by competing on the binding with HIF-1alpha to CBP/p300. CITED2 is essential for Mouse Fetal liver haematopoiesis and also mandatory for the appropriate formation of the hyaloid vasculature and for lens morphogenesis as well. CITED2 is recognized for its relations with transcriptional coactivators, such as CBP and p300 and also takes part in various biological processes, together with cardiovascular development, metabolism, as well as response to hypoxia. Moreover, the most valuable form of CITED2 for learning its functional roles & potential applications in cancer research and regenerative medicine is the Recombinant one which is produced by molecular cloning and expression systems. | |
| Precautions | |
| CISD1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9NZ45 ) | |
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ADMEbio Team
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