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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0467-5 | 7 days | 5 µg | $120.00 |
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| RCP0467-20 | 7 days | 20 µg | $290.00 | |||
| RCP0467-1 | 7 days | 1 mg | $5,760.00 |
Product Overview | |
| Name | CMC4 Human |
|---|---|
| Description | |
| CX9C Motif Containing 4 Human Recombinant | |
| Accession (Primary) | P56277 |
| Synonyms | |
| UMP-CMP kinase, Cytidine monophosphate kinase, Cytidylate kinase, Deoxycytidylate kinase, Uridine monophosphate kinase, Uridine monophosphate/cytidine monophosphate kinase, UMP/CMP kinase, UMP/CMPK, CMPK1, CMK, CMPK, UCK, UMK, UMPK, UMP-CMPK, RP11-511I2.1. | |
| Introduction | |
| UMP-CMP kinase and deoxycytidylate kinase (CMPK1) is an enzyme which catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction brings about the formation of ADP and the corresponding nucleoside diphosphate that are necessary for cellular nucleic acid synthesis. In addition, CMPK1 has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| CMPK1 solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 1mM DTT and 100mM NaCl. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Av oid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MLSRCRSGLL HVLGLSFLLQ TRRPILLCSP RLMKPLVVFV LGGPGAGKGT QCARIVEKYG YTHLSAGELL RDERKNPDSQ YGELIEKYIK EGKIVPVEIT ISLLKREMDQ TMAANAQKNK FLIDGFPRNQ DNLQGWNKTM DGKADVSFVL FFDCNNEICI ERCLERGKSS GRSDDNRESL EKRIQTYLQS TKPIIDLYEE MGKVKKIDAS KSVDEVFDEV VQIFDKEG. | |
| Precautions | |
| CMC4 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P56277 ) | |
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ADMEbio Team
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ADMEbio Team
