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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0528-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP0528-10 | 7 days | 10 µg | $290.00 | |||
| RCP0528-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | CRISP3 Human |
|---|---|
| Description | |
| Cysteine-Rich Secretory Protein 3 Human Recombinant | |
| Accession (Primary) | P54108 |
| Synonyms | |
| Adapter molecule crk, Proto-oncogene c-Crk, p38, CRK, CRKII. | |
| Introduction | |
| CRK belongs to the signaling adapter protein family which binds to several tyrosine-phosphorylated proteins. CRK is involved in many cellular processes such as apoptosis, proliferation, and differentiation. CRK has a modular domain architecture consisting of an SH2 followed by two SH3 domains (src-homology domains). The N-terminal SH2 domain of the CRK protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colorless solution. | |
| Formulation | |
| The CRK solution (0.5 mg/ml) contains 20mM Tris-HCl Buffer (pH 8.0) and 10% Glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 95.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR SRQGSGVILR QEEAEYVRAL FDFNGNDEED LPFKKGDILR IRDKPEEQWW NAEDSEGKRG MIPVPYVEKY RPASASVSAL IGGR. | |
| Precautions | |
| CRISP3 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P54108 ) | |
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ADMEbio Team
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