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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0576-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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| RCP0576-20 | 7 days | 20 µg | $290.00 | |||
| RCP0576-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | CST9 Human |
|---|---|
| Description | |
| Cystatin 9 Human Recombinant | |
| Accession (Primary) | Q5W186 |
| Immunogen | |
| Anti-human CSTA mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CSTA protein 1-98 amino acids purified from E. coli. | |
| Synonyms | |
| Cystatin-A, Cystatin-AS, Stefin-A, CSTA, STF1, STFA. | |
| Introduction | |
| Cystatin-A is the intracellular inhibitor of cysteine proteinase cathepsin B (CatB) and belongs to family 1 of the cystatin superfamily of inhibitor proteins. CSTA is a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. It has been proposed that extracellular CatB together with other classes of proteinases are all subjected to a cascade-like manner of activation. CatB and its inhibitor Cystatin-A are involved in degradation of extracellular matrix proteins during tissue remodeling. CSTA is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Cystatin-A has been reported to be found in high concentrations in epithelial cells, polymorphonuclear leukocytes and lymphoid tissue. Stefins may be used as prognostic and diagnostic tools for cancer. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide. | |
| Applications | |
| The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| PAT1B12AT. | |
| Ig Subclass | |
| Mouse IgG 1 heavy chain and k light chain. | |
| Purification Method | |
| CSTA antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. | |
| Storage Procedures | |
| For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. | |
| Stability / Shelf Life | |
| 12 months at -20°C. 1 month at 4°C. | |
| Precautions | |
| CST9 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q5W186 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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ADMEbio Team
