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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0586-2 | 7 days | 2 µg | $120.00 |
Select product before adding to cart
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| RCP0586-10 | 7 days | 10 µg | $290.00 | |||
| RCP0586-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | CTHRC1 Human, Sf9 |
|---|---|
| Description | |
| Collagen Triple Helix Repeat Containing 1 Human Recombinant, Sf9 | |
| Accession (Primary) | Q96CG8 |
| Immunogen | |
| mixture of mouse activated T cells. | |
| Synonyms | |
| GSE, CD152, IDDM12, CELIAC3, CTLA-4. | |
| Introduction | |
| CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Blocking and staining antibody. For staining, use for blocking CTLA-4 function should be determined by the investigator. | |
| Type | |
| Hamster Anti Mouse Monoclonal. | |
| Clone | |
| RYNmCTLA-4. | |
| Ig Subclass | |
| Hamster IgG. | |
| Purification Method | |
| Ion exchange column. | |
| Storage Procedures | |
| Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | |
| Available Conjugates | |
| This antibody is only available as purified antibody. | |
| Precautions | |
| CTHRC1 Human, Sf9 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q96CG8 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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Thank you,
ADMEbio Team
