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CUEDC2 Human

CUE Domain Containing 2 Human Recombinant

 
Catalog #
RCP0590
Uniprot Id
Q9H467
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
RCP0590-5 7 days 5 µg $120.00
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RCP0590-20 7 days 20 µg $290.00
RCP0590-1 7 days 1 mg $4,320.00
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Product Overview

NameCUEDC2 Human
Description
CUE Domain Containing 2 Human Recombinant
Accession (Primary)Q9H467
Synonyms
Cullin 1, CUL-1, Cullin-1
Introduction
Cullin1, is an essential component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, that facilitate the ubiquitination of proteins which take part in cell cycle progression, signal transduction and transcription. In the SCF complex. Cullin1 assists in a rigid scaffold which organizes the SKP1-F-box protein and RBX1 subunits. Cullin1 contributes to catalysis by positioning of the substrate and the ubiquitin-conjugating enzyme.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered clear solution.
Formulation
The CUL1 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 1mM DTT, 100mM NaCl and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MSSTRSQNPH GLKQIGLDQI WDDLRAGIQQ VYTRQSMAKS RYMELYTHVY NYCTSVHQSN QARGAGVPPS KSKKGQTPGG AQFVGLELYK RLKEFLKNYL TNLLKDGEDL MDESVLKFYT QQWEDYRFSS KVLNGICAYL NRHWVRRECD EGRKGIYEIY SLALVTWRDC LFRPLNKQVT NAVLKLIEKE RNGETINTRL ISGVVQSYVE LGLNEDDAFA KGPTLTVYKE SFESQFLADT ERFYTRESTE FLQQNPVTEY MKKAEARLLE EQRRVQVYLH ESTQDELARK CEQVLIEKHL EIFHTEFQNL LDADKNEDLG RMYNLVSRIQ DGLGELKKLL ETHIHNQGLA AIEKCGEAAL NDPKMYVQTV LDVHKKYNAL VMSAFNNDAG FVAALDKACG RFINNNAVTK
Precautions
CUEDC2 Human is for research use only and not for use in diagnostic or therapeutic procedures.

Target Information: ( Q9H467 )

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