| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0601-5 | 7 days | 5 µg | $120.00 |
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| RCP0601-20 | 7 days | 20 µg | $290.00 | |||
| RCP0601-1 | 7 days | 1 mg | $4,320.00 |
Product Overview | |
| Name | CYP2E1 Human |
|---|---|
| Description | |
| Cytochrome P450 2E1 Human Recombinant | |
| Accession (Primary) | P05181 |
| Synonyms | |
| CYR61, Protein CYR61, Cysteine-rich angiogenic inducer 61, IGF-binding protein 10, IGFBP-10, IBP-10, Protein GIG1, CCN family member 1, CCN1, GIG1, IGFBP10. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| Each mg was lyophilized with 1xPBS, 0.4% SDS and 4mM DTT. | |
| Stability | |
| Store lyophilized CYR61at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. | |
| Purity | |
| Greater than 90% as determined by SDS-PAGE. | |
| Solubility | |
| It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture. | |
| Background | |
| Cysteine-Rich Angiogenic Inducer 61 also known as CYR61 is a growth factor-inducible, immediate-early gene which has many activities in various cancers. CYR61 is a part of to the CCN family a group of secreted extracellular matrix-associated proteins which regulate diverse biological processes including cell adhesion, proliferation, migration, survival and angiogenesis. CYR61 plays a significant role in development, tissue repair, wound healing, and various pathological conditions such as cancer and fibrosis. CYR61 is encoded by a growth factor-inducible immediate-early gene. CYR61 promotes the adhesion of endothelial cells by interaction with integrin and enhances growth factor-induced DNA synthesis in the same cell type. | |
| Precautions | |
| CYP2E1 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P05181 ) | |
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