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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0615-2 | 7 days | 2 µg | $120.00 |
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| RCP0615-10 | 7 days | 10 µg | $290.00 | |||
| RCP0615-1 | 7 days | 1 mg | $8,320.00 |
Product Overview | |
| Name | DBNDD2 Human |
|---|---|
| Description | |
| Dysbindin (Dystrobrevin Binding Protein 1) Domain Containing 2 Human Recombinant | |
| Accession (Primary) | Q9BQY9 |
| Synonyms | |
| Debranching RNA Lariats 1, Lariat Debranching Enzyme, Debranching Enzyme Homolog 1, RNA Lariat Debranching Enzyme, EC 3.1.-.-. | |
| Introduction | |
| DBR1 is an RNA lariat debranching enzyme which hydrolyzes 2'-5' prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of eliminated lariat intron RNA, transforming them to linear molecules which are then degraded. Additionally, DBR1 takes part in retroviral replication. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered clear solution. | |
| Formulation | |
| The DBR1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.15M NaCl, 1mM DTT and 20% glycerol. | |
| Stability | |
| Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | |
| Purity | |
| Greater than 90.0% as determined by SDS-PAGE. | |
| Amino acid sequence | |
| MGSSHHHHHH SSGLVPRGSH MGS HVKFAAL MQHQAKDKGQ TARATKFLAL DKCLPHRDFL QILEIEHDPS APDYLEYDIE WLTILRATDD LINVTGRLWN MPENNGLHAR WDYSATEEGM KEVLEKLNHD LKVPCNFSVT AACYDPSKPQ TQMQLIHRIN PQTTEFCAQL GIIDINVRLQ KSKEEHHVCG EYEEQDDVES NDSGEDQSEY NTDTSALSSI NPDEIMLDEE EDEDSIVSAH SGMNTPSVEP SDQASEFSAS FSDVRILPGS MIVSSDDTVD STIDREGKPG GTVESGNGED LTKVPLKRLS DEHEPEQRKK IKRRNQAIYA AVDDDDDDAA | |
| Precautions | |
| DBNDD2 Human is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( Q9BQY9 ) | |
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ADMEbio Team
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