| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| RCP0634-100 | 7 days | 100 µg | $330.00 |
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| RCP0634-500 | 7 days | 500 µg | $1,320.00 | |||
| RCP0634-1000 | 7 days | 1000 µg | $2,160.00 |
Product Overview | |
| Name | Der F1 |
|---|---|
| Description | |
| Der F1 Mosaic Protein Recombinant | |
| Accession (Primary) | P16311 |
| Synonyms | |
| Peptidase 1, Major mite fecal allergen Der p 1, Allergen Der p I, Der p 1, DERP1, Der-P1. | |
| Introduction | |
| DERP1 is a thiol protease, with a preference for substrates with a large hydrophobic side chain in the P2 position, or with basic residues. DERP1 is a C1 peptidase family member. DERP1 has extensive endopeptidase specificity. DERP1 is N-glycosylated. N-glycanase treatment does not completely remove carbohydrates, suggesting that the protein contains additional glycosylation sites. DERP1 causes an allergic reaction in humans. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis. DERP1 binds to IgE in 80% of patients with house dust allergy. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile filtered colorless solution. | |
| Formulation | |
| 60mM NaCl and 50mM Tris-HCl pH 8.0. | |
| Stability | |
| Der-P1 although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. | |
| Purity | |
| Protein is >95% pure as determined by 10% SDS-PAGE (coomassie staining). | |
| Amino acid sequence | |
| MSIKTFEEYKKAFNKSYATFEDEEAARKNFLESVKYVQSNGGAINHLSDLSLDEFK NRFLMSAEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSAWAFS GVAATESAYLAYRNQSLDLAEQELVDCASQHGCHGDTIPRGIEYIQHNGVVQESYYRYVA REQSCRRPNAQRFGISNYCQIYPPNVNKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTI IQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIEEYPY VVILHHHHHH. | |
| Purification Method | |
| Purified by proprietary chromatographic technique. | |
| Precautions | |
| Der F1 is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( P16311 ) | |
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